In order to find this out, you may check it on your computer. 'we tested Spyder3 on a few Windows 10 machines, however, depending upon your computer's configuration, the software may run or not run. This is what Datacolor wrote in their answer: Comparing the two profiles, Spyder3 had cut me a lot of greens compared to sRGB and the Spyder5 profile was much better.
So I contacted Datacolor and in the end I bought a Spyder5 with 30% discount and I even got a lenscal with it. It worked, did calibrations etc., but I had the impression that something was wrong.
I had the same situation: I had upgraded to Win10 and used my Spyder3 there.
